OR2T1

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Olfactory receptor, family 2, subfamily T, member 1
Identifiers
Symbols	OR2T1; OR1-25
External IDs	MGI: 109304 HomoloGene: 74028 GeneCards: OR2T1 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus Sources: Amigo / EGO
Orthologs
Species	Human	Mouse
Entrez	26696	18330
Ensembl	ENSG00000175143	ENSMUSG00000072707
UniProt	O43869	n/a
RefSeq (mRNA)	NM_030904	NM_147027
RefSeq (protein)	NP_112166	NP_667238
Location (UCSC)	Chr 1: 246.64 - 246.64 Mb	Chr 14: 13.12 - 13.12 Mb
PubMed search	[1]	[2]

Olfactory receptor 2T1 is a protein that in humans is encoded by the OR2T1 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Fuchs T, Malecova B, Linhart C; et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052. CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR2T1+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.