OR51B4

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Olfactory receptor, family 51, subfamily B, member 4
Identifiers
Symbols	OR51B4; HOR5'Beta1
External IDs	MGI: 1341906 HomoloGene: 88376 GeneCards: OR51B4 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus Sources: Amigo / EGO
Orthologs
Species	Human	Mouse
Entrez	79339	18367
Ensembl	ENSG00000183251	ENSMUSG00000058200
UniProt	Q9Y5P0	n/a
RefSeq (mRNA)	NM_033179	NM_013618
RefSeq (protein)	NP_149419	NP_038646
Location (UCSC)	Chr 11: 5.28 - 5.28 Mb	Chr 7: 103.76 - 103.76 Mb
PubMed search	[1]	[2]

Olfactory receptor 51B4 is a protein that in humans is encoded by the OR51B4 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Bulger M, van Doorninck JH, Saitoh N; et al. (1999). "Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes". Proc. Natl. Acad. Sci. U.S.A. 96 (9): 5129–34. doi:10.1073/pnas.96.9.5129. PMC 21828 Freely accessible. PMID 10220430. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bulger M, Bender MA, van Doorninck JH; et al. (2001). "Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters". Proc. Natl. Acad. Sci. U.S.A. 97 (26): 14560–5. doi:10.1073/pnas.97.26.14560. PMC 18958 Freely accessible. PMID 11121057. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR51B4+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.