OR2AE1

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Olfactory receptor, family 2, subfamily AE, member 1
Identifiers
SymbolsOR2AE1; OR2AE2
External IDsMGI3030004 HomoloGene79678 GeneCards: OR2AE1 Gene
RNA expression pattern
250px
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez81392258959
EnsemblENSG00000176607ENSMUSG00000062245
UniProtQ8NHA4n/a
RefSeq (mRNA)NM_001005276NM_146957
RefSeq (protein)NP_001005276NP_667168
Location (UCSC)Chr 7:
99.31 - 99.31 Mb
Chr 16:
19.52 - 19.52 Mb
PubMed search[1][2]

Olfactory receptor 2AE1 is a protein that in humans is encoded by the OR2AE1 gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

See also

References

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Further reading

  • "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. 1999. PMID 9847074. 
  • Thompson EE, Kuttab-Boulos H, Yang L; et al. (2006). "Sequence diversity and haplotype structure at the human CYP3A cluster". Pharmacogenomics J. 6 (2): 105–14. doi:10.1038/sj.tpj.6500347. PMID 16314882. 

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

  1. 1.0 1.1 "Entrez Gene: OR2AE1 olfactory receptor, family 2, subfamily AE, member 1".