OR51E2

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Olfactory receptor, family 51, subfamily E, member 2
Identifiers
Symbols	OR51E2; OR51E3P; OR52A2; PSGR
External IDs	MGI: 2157548 HomoloGene: 23713 GeneCards: OR51E2 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus Sources: Amigo / EGO
RNA expression pattern
250px
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	81285	170639
Ensembl	ENSG00000167332	ENSMUSG00000043366
UniProt	Q9H255	n/a
RefSeq (mRNA)	NM_030774	NM_130866
RefSeq (protein)	NP_110401	NP_570936
Location (UCSC)	Chr 11: 4.66 - 4.68 Mb	Chr 7: 102.61 - 102.63 Mb
PubMed search	[1]	[2]

Olfactory receptor 51E2 is a protein that in humans is encoded by the OR51E2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Adams MD, Kerlavage AR, Fleischmann RD; et al. (1995). "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence". Nature. 377 (6547 Suppl): 3–174. doi:10.1038/377003a0. PMID 7566098. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Xia C, Ma W, Wang F; et al. (2001). "Identification of a prostate-specific G-protein coupled receptor in prostate cancer". Oncogene. 20 (41): 5903–7. doi:10.1038/sj.onc.1204803. PMID 11593396. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yuan TT, Toy P, McClary JA; et al. (2002). "Cloning and genetic characterization of an evolutionarily conserved human olfactory receptor that is differentially expressed across species". Gene. 278 (1-2): 41–51. doi:10.1016/S0378-1119(01)00709-0. PMID 11707321. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052. CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Weng J, Wang J, Cai Y; et al. (2005). "Increased expression of prostate-specific G-protein-coupled receptor in human prostate intraepithelial neoplasia and prostate cancers". Int. J. Cancer. 113 (5): 811–8. doi:10.1002/ijc.20635. PMID 15499628. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Weng J, Ma W, Mitchell D; et al. (2006). "Regulation of human prostate-specific G-protein coupled receptor, PSGR, by two distinct promoters and growth factors". J. Cell. Biochem. 96 (5): 1034–48. doi:10.1002/jcb.20600. PMID 16149059. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Xu LL, Sun C, Petrovics G; et al. (2006). "Quantitative expression profile of PSGR in prostate cancer". Prostate Cancer Prostatic Dis. 9 (1): 56–61. doi:10.1038/sj.pcan.4500836. PMID 16231015. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang J, Weng J, Cai Y; et al. (2006). "The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase". Prostate. 66 (8): 847–57. doi:10.1002/pros.20389. PMID 16491480. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR51E2+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.