OR2D2

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Olfactory receptor, family 2, subfamily D, member 2
Identifiers
Symbols	OR2D2; OR11-610; OR2D1; hg27
External IDs	OMIM: 608494 MGI: 3030549 HomoloGene: 81541 GeneCards: OR2D2 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus Sources: Amigo / EGO
Orthologs
Species	Human	Mouse
Entrez	120776	258776
Ensembl	ENSG00000166368	ENSMUSG00000062987
UniProt	Q9H210	n/a
RefSeq (mRNA)	NM_003700	NM_146780
RefSeq (protein)	NP_003691	NP_666991
Location (UCSC)	Chr 11: 6.87 - 6.87 Mb	Chr 7: 106.92 - 106.92 Mb
PubMed search	[1]	[2]

Olfactory receptor 2D2 is a protein that in humans is encoded by the OR2D2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Fuchs T, Malecova B, Linhart C; et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052. CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR2D2+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.