OR52I2

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Olfactory receptor, family 52, subfamily I, member 2
Identifiers
Symbols	OR52I2; OR11-12
External IDs	MGI: 3030390 HomoloGene: 17380 GeneCards: OR52I2 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus Sources: Amigo / EGO
Orthologs
Species	Human	Mouse
Entrez	143502	258749
Ensembl	ENSG00000175609	ENSMUSG00000073969
UniProt	Q8NH67	n/a
RefSeq (mRNA)	NM_001005170	NM_146754
RefSeq (protein)	NP_001005170	NP_666965
Location (UCSC)	Chr 11: 4.56 - 4.57 Mb	Chr 7: 102.54 - 102.54 Mb
PubMed search	[1]	[2]

Olfactory receptor 52I2 is a protein that in humans is encoded by the OR52I2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052. CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR52I2+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.