OR10A4
| edit |
| Olfactory receptor, family 10, subfamily A, member 4 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | OR10A4; JCG5; OR10A4P | ||||||||||||
| External IDs | MGI: 109148 HomoloGene: 23241 GeneCards: OR10A4 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 283297 | 18314 | |||||||||||
| Ensembl | ENSG00000170782 | ENSMUSG00000073897 | |||||||||||
| UniProt | Q9H209 | n/a | |||||||||||
| RefSeq (mRNA) | NM_207186 | NM_020598 | |||||||||||
| RefSeq (protein) | NP_997069 | NP_065623 | |||||||||||
| Location (UCSC) | Chr 11: 6.85 - 6.86 Mb | Chr 7: 106.89 - 106.89 Mb | |||||||||||
| PubMed search | [1] | [2] | |||||||||||
Olfactory receptor 10A4 is a protein that in humans is encoded by the OR10A4 gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
See also
References
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<references />, or <references group="..." />Further reading
- Lane RP, Cutforth T, Young J; et al. (2001). "Genomic analysis of orthologous mouse and human olfactory receptor loci". Proc. Natl. Acad. Sci. U.S.A. 98 (13): 7390–5. doi:10.1073/pnas.131215398. PMC 34679 Freely accessible. PMID 11416212.
- Gaudin JC, Breuils L, Haertlé T (2002). "New GPCRs from a human lingual cDNA library". Chem. Senses. 26 (9): 1157–66. doi:10.1093/chemse/26.9.1157. PMID 11705801.
- Fuchs T, Malecova B, Linhart C; et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052.
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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