OR4F6

edit

Olfactory receptor, family 4, subfamily F, member 6
Identifiers
Symbols	OR4F6; OR15-15; OR4F12
External IDs	MGI: 3031144 HomoloGene: 64876 GeneCards: OR4F6 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus Sources: Amigo / EGO
RNA expression pattern
250px
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	390648	258441
Ensembl	ENSG00000184140	ENSMUSG00000074949
UniProt	Q8NGB9	n/a
RefSeq (mRNA)	NM_001005326	NM_146449
RefSeq (protein)	NP_001005326	NP_666660
Location (UCSC)	Chr 15: 100.16 - 100.16 Mb	Chr 2: 111.81 - 111.81 Mb
PubMed search	[1]	[2]

Olfactory receptor 4F6 is a protein that in humans is encoded by the OR4F6 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052. CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR4F6+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.