Dacemazine

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Dacemazine
260px
Systematic (IUPAC) name
2-dimethylamino-1-phenothiazin-10-ylethanone
Identifiers
CAS Number 518-61-6
ATC code none
PubChem CID 68846
ChemSpider 62079
Chemical data
Formula C16H16N2OS
Molar mass 284.376 g/mol[[Script error: No such module "String".]]
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Dacemazine (INN, also known as Ahistan and Histantine)[1] is a phenothiazine derivative which acts as an histamine antagonist at the H1 subtype. First described in 1951, it was never marketed as a drug on its own, although a combination of dacemazine and di-tert-butylnaphthalenesulfonate was sold as an antispasmodic and antitussive under the trade name Codopectyl.[1] It was also assessed as a possible anticancer drug.[2]

References

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  1. 1.0 1.1 Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found. Retrieved on August 2, 2008 through Google Book Search.
  2. Karolyhazy G, Havas I, Jansco G, Kapas L, Sellei C. The anticarcinogenic effect of dimethylaminoacetyl-phentiazide (ahistan). Kiserletes Orvostudomany. 1952 Aug;4(4):260-2. PMID 13023855