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Systematic (IUPAC) name
N,N-dimethyl-3-(6-phenyl-11H-pyrido[2,3-b][1,4]benzodiazepin-11-yl)propan-1-amine (2E)-but-2-enedioate
Clinical data
Routes of
Legal status
Legal status
  • Uncontrolled
CAS Number 83166-18-1
ATC code none
PubChem CID 6450479
ChemSpider 4953084
Chemical data
Formula C27H28N4O4
Molar mass 472.54 g/mol[[Script error: No such module "String".]]
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Tampramine (AHR-9,377) is a tricyclic antidepressant (TCA) which was developed in the 1980s but was never marketed.[1][2] Despite being a TCA, it acts as a selective norepinephrine reuptake inhibitor and has negligible affinity for adrenergic, histaminergic, and muscarinic receptors.[1] It was found to be effective in the forced swim test (FST) model of depression in animal studies but is not known to have ever been trialed in humans.[2]

See also


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  2. 2.0 2.1 O'Donnell JM, Seiden LS (1985). "Effect of the experimental antidepressant AHR-9377 on performance during differential reinforcement of low response rate". Psychopharmacology. 87 (3): 283–5. PMID 3936083.