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Pargyline (Eutonyl) is a monoamine oxidase B (MAO-B) inhibitor.[1] It has antihypertensive effects.[2]
Pharmacology
It functions by inhibiting the metabolism of catecholamines and tyramine within presynaptic nerve terminals. Patients taking pargyline must avoid concurrent consumption of tyramine-containing foods such as blue cheese and beer, as this can lead to a hypertensive crisis.[3]
References
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anat(s,m,p,4,e,b,d,c,a,f,l,g)/phys/devp/cell
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- ↑ Murphy DL, Karoum F, Pickar D; et al. (1998). "Differential trace amine alterations in individuals receiving acetylenic inhibitors of MAO-A (clorgyline) or MAO-B (selegiline and pargyline)". J. Neural Transm. Suppl. 52: 39–48. PMID 9564606.
- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
- ↑ Tulane University School of Medicine Department of Pharmacology: Autonomic Drug Profile handout, October 2006
