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Systematic (IUPAC) name
Legal status
Legal status
  • Legal
CAS Number 87913-26-6
ATC code none
PubChem CID 4660557
Chemical data
Formula C16H20BrN
Molar mass 306.246 g/mol[[Script error: No such module "String".]]
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Bromantane is a stimulant drug developed in Russia during the late 1980s,[1][2] which acts mainly by inhibiting the reuptake of both dopamine and serotonin in the brain,[3][4][5][6] although it also has anticholinergic effects at very high doses.[7][8] It was used as a doping agent to enhance athletic performance, and several athletes tested positive for the drug at the 1996 Atlanta Olympic Games,[9] following which it was added to the banned list. Research on this class of drugs has been fairly extensive and a large family of derivatives are known, although bromantane remains the best studied,[10] and human trials continue for applications such as increasing endurance under extreme conditions.[11]


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  1. Krapivin SV, Sergeeva SA, Morozov IS. A quantitative pharmaco-electroencephalographic analysis of the action of bromantane. (Russian) Biulleten Eksperimental'noi Biologii i Meditsiny. 1993 Nov;116(11):515-8. PMID 8312546
  2. I.S. Morozov, I.A. Ivanova and T.A. Lukicheva (2001). "Search for New Drugs: Actoprotector and Adaptogen properties of Adamantane Derivatives (A Review)". Pharma. Chem. J. 35: 235–238. doi:10.1023/A:1011905302667. 
  3. Grekhova TV, Gaĭnetdinov RR, Sotnikova TD, Krasnykh LM, Kudrin VS, Sergeeva SA, Morozov IS. The effect of bromantane, a new immunostimulant with psychostimulating action, on release and metabolism of dopamine in the dorsal striatum of freely moving rats: a microdialysis study. (Russian) Biulleten Eksperimental'noi Biologii i Meditsiny. 1995 Mar;119(3):302-4. PMID 7795203
  4. Kudrin VS, Sergeeva SA, Krasnykh LM, Miroshnichenko II, Grekhova TV, Gaĭnetdinov RR. The effect of bromantane on the dopamin- and serotoninergic systems of the rat brain. (Russian) Eksperimental'naia i Klinicheskaia Farmakologiia. 1995 Jul-Aug;58(4):8-11. PMID 7580761
  5. Morozov IS, Pukhova GS, Avdulov NA, Sergeeva SA, Spasov AA, Iezhitsa IN. The mechanisms of the neurotropic action of bromantan. (Russian) Eksperimental'naia i Klinicheskaia Farmakologiia. 1999 Jan-Feb;62(1):11-4. PMID 10198757
  6. Seredenin SB, Miramedova AG. Analysis of pharmacological properties of bromantane. (Russian) Biulleten Eksperimental'noi Biologii i Meditsiny. 1999 Nov;128(11):529-31. PMID 10640239
  7. Bugaeva LI, Verovskiĭ VE, Iezhitsa IN, Spasov AA. An acute toxicity study of bromantane. (Russian) Eksperimental'naia i Klinicheskaia Farmakologiia. 2000 Jan-Feb;63(1):57-61. PMID 10763112
  8. Iezhitsa IN, Spasov AA, Bugaeva LI, Morozov IS. Toxic effect of single treatment with bromantane on neurological status of experimental animals. (Russian) Biulleten Eksperimental'noi Biologii i Meditsiny. 2002 Apr;133(4):380-3. PMID 12124651
  9. Burnat P, Payen A, Le Brumant-Payen C, Hugon M, Ceppa F. Bromontan, a new doping agent. Lancet. 1997 Sep 27;350(9082):963-4. PMID 9314900
  10. Morozov IS, Klimova NV, Sergeeva SA, Ivanova IA, Barchukov VG, Kovalev GI, Piatin BM, Avdiunina NI. Adamantane derivatives enhancing body's resistance to emergencies. (Russian) Vestnik Rossiiskoi Akademii Meditsinskikh Nauk. 1999;(3):28-32. PMID 10222828
  11. Viatleva OA, Barchukov VG, Morozov IS, Salenko IuA, Zhirnov EN. The neuro- and psychophysiological effects of bromantane. (Russian) Voenno-Meditsinskii Zhurnal. 2000 Aug;321(8):61-5, 96. PMID 10998997