Flurbiprofen
From Self-sufficiency
| 200px | |
| Systematic (IUPAC) name | |
|---|---|
|
(RS)-2-(2-fluorobiphenyl-4-yl)propanoic acid | |
| Clinical data | |
| Pregnancy category | |
| Routes of administration | Oral |
| Legal status | |
| Legal status |
|
| Pharmacokinetic data | |
| Protein binding | > 99% |
| Metabolism | Hepatic (CYP2C9) |
| Biological half-life | 4.7-5.7 hours |
| Excretion | Renal |
| Identifiers | |
| CAS Number | 5104-49-4 |
| ATC code | M01AE09 (WHO) , M02AA19, R02AX01, S01BC04 |
| PubChem | CID 3394 |
| DrugBank | APRD00753 |
| Synonyms | (±)-2-fluoro-α-methyl-(1,1'-biphenyl)-4-acetic acid |
| Chemical data | |
| Formula | C15H13FO2 |
| Molar mass | 244.261 g/mol[[Script error: No such module "String".]] |
| Script error: No such module "collapsible list". | |
| Physical data | |
| Melting point | 117 °C (243 °F) |
| (verify) | |
Flurbiprofen is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs) used to treat the inflammation and pain of arthritis. [1] It is known by the following tradenames: Ansaid, marketed by Pfizer, Flurwood by W.Woodward and Froben, by Abbott. Flurbiprofen is also used as an active ingredient in some kinds of throat lozenges (Strepsils Intensive).
A single enantiomer of racemate flurbiprofen, tarenflurbil [(R)-flurbiprofen)], is currently in clinical trials for the treatment of metastatic prostate cancer.
References
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de:Flurbiprofen it:Flurbiprofene ja:フルルビプロフェン pl:Flurbiprofen ro:Flurbiprofen
tr:Flurbiprofen- ↑ "Medical Dictionary, Houghton Mifflin Company". retrieved July 21, 2010. Check date values in:
|date=(help)
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