CGS-9896

From Self-sufficiency
Jump to: navigation, search
CGS-9896
180px
Systematic (IUPAC) name
2-(4-chlorophenyl)-1H-pyrazolo[4,5-c]quinolin-3-one
Identifiers
CAS Number 77779-36-3
PubChem CID 108030
Chemical data
Formula C16H10ClN3O
Molar mass 295.7231 g/mol[[Script error: No such module "String".]]
Script error: No such module "collapsible list".
Script error: No such module "TemplatePar".Expression error: Unexpected < operator.

CGS-9896 is an anxiolytic drug used in scientific research. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic.[1]

CGS-9896 is a benzodiazepine receptor partial agonist, which produces long-lasting anxiolytic and anticonvulsant effects in animal studies, but does not produce sedative effects.[2][3] It also increases appetite,[4] and reduces the development of gastrointestinal ulcers following chronic stress.[5]

References

Cite error: Invalid <references> tag; parameter "group" is allowed only.

Use <references />, or <references group="..." />


  1. Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
  2. Bernasconi R, Marescaux C, Vergnes M; et al. (1988). "Evaluation of the anticonvulsant and biochemical activity of CGS 8216 and CGS 9896 in animal models". J Neural Transm. 71 (1): 11–27. doi:10.1007/BF01259406. PMID 3343593. 
  3. Rump S, Raszewski W, Gidynska T, Galecka E (1990). "Effects of CGS 9896 in acute experimental intoxication with fluostigmine". Arch Toxicol. 64 (5): 412–3. doi:10.1007/BF01973465. PMID 2206111. 
  4. Chen SW, Davies MF, Loew GH (1995). "Food palatability and hunger modulated effects of CGS 9896 and CGS 8216 on food intake". Pharmacol Biochem Behav. 51 (2-3): 499–503. doi:10.1016/0091-3057(95)00020-W. PMID 7667375. 
  5. Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.