DAA-1097

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DAA-1097
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Systematic (IUPAC) name
N-(4-chloro-2-phenoxyphenyl)-N-(2-isopropoxybenzyl)acetamide
Identifiers
CAS Number 220551-79-1
PubChem CID 9844410
Chemical data
Formula C24H24ClNO3
Molar mass 409.904 g/mol[[Script error: No such module "String".]]
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DAA-1097 is a drug which acts as a potent and selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO, but with no affinity at central benzodiazepine receptors. It has anxiolytic effects in animal studies.[1][2][3]


References

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  1. Okuyama S, Chaki S, Yoshikawa R, Ogawa S, Suzuki Y, Okubo T, Nakazato A, Nagamine M, Tomisawa K (1999). "Neuropharmacological profile of peripheral benzodiazepine receptor agonists, DAA1097 and DAA1106". Life Sciences. 64 (16): 1455–64. doi:10.1016/S0024-3205(99)00079-X. PMID 10321725. 
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  3. James ML, Selleri S, Kassiou M (2006). "Development of ligands for the peripheral benzodiazepine receptor". Current Medicinal Chemistry. 13 (17): 1991–2001. doi:10.2174/092986706777584979. PMID 16842193.