Oxanamide

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Oxanamide
File:Oxanamide.png
Systematic (IUPAC) name
2-ethyl-3-propyloxirane-2-carboxamide
Identifiers
CAS Number 126-93-2
ATC code none
PubChem CID 31365
Chemical data
Formula C8H15NO2
Molar mass 157.21 g/mol[[Script error: No such module "String".]]
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Oxanamide (Quiactin) is an anxiolytic and muscle relaxant which can produce sedative and hypnotic effects in sufficiently high doses.[1] An uncontrolled trial on patients treated in a clinical gynecology practice published in 1959 found that oxanamide was efficacious in the treatment of anxiety resulting from premenstrual syndrome, menopause, and various other causes, with minimal sedation or other side effects.[2]

References

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GABAA PAMs
Others
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5-HT1A Agonists
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mGluR5 NAMs
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M: PSO/PSI

dsrd (o, p, m, p, a, d, s), sysi/epon, spvo

proc, drug(N5A/5B/5C/6A/6B/6D)

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ungrouped
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M: PSO/PSI

dsrd (o, p, m, p, a, d, s), sysi/epon, spvo

proc, drug(N5A/5B/5C/6A/6B/6D)

Peripherally acting
(primarily antinicotinic,
Neuromuscular junction block)
Tertiary amines / Non-curare alkaloids
ultra-short duration: Gantacurium

short duration: Mivacurium  · Chandonium

intermediate duration: Atracurium  · Cisatracurium  · Fazadinium  · Rocuronium  · Vecuronium  · Dipyrandium  · N,N'-Dimethylconessine  · Stercuronium  · Dacuronium  · Mytolon

long duration: Doxacurium · Dimethyltubocurarine · Pancuronium · Pipecuronium  · Laudexium  · Gallamine  · Benzoquinonium  · Decaethonium  · Succinyl-bis-β-phenylcholine  · Anatruxonium  · Truxilonium  · Cyclobutonium  · Dipyronium · Pyrocurinum  · Tercuronium  · Diadonium

unsorted: Hexafluronium (Hexafluorenium)  · Myanesin  · Cyclobutonium  · Mebutanium  · Amidonium  · Nubitanium  · Quilidium  · Decadonium
Clostridium botulinum toxin  · Atraxotoxin  · β-Bungarotoxin  · Black widow spider venom
Centrally acting
Other
Directly acting

M: MUS, DF+DRCT

anat (h/n, u, t/d, a/p, l)/phys/hist

noco(m, s, c)/cong(d)/tumr, sysi/epon, injr

proc, drug (M1A/3)


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  1. ↑ Kuhn, WL; Ketteler, HJ; Van Maanen, EF (1960). "Effects of oxanamide on the central nervous system". Proceedings of the Society for Experimental Biology and Medicine. 103: 101–3. PMID 14412594. 
  2. ↑ Robert B. Woodhull (1959). "Oxanamide; adjunctive use of a new tranquilizer in gynecology". California Medicine. 90 (4): 275–7. PMC 1577644 Freely accessible. PMID 13638840. 
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