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Systematic (IUPAC) name
7-chloro- 5-phenyl- 1-(2,2,2-trifluoroethyl) -1,3-dihydro- 2H-1,4-benzodiazepin- 2-one
Clinical data
  •  ?
Routes of
Legal status
Legal status
Pharmacokinetic data
Bioavailability ?
Metabolism Hepatic
Biological half-life ?
Excretion Renal
CAS Number 23092-17-3
ATC code N05BA13 (WHO)
PubChem CID 31640
DrugBank APRD01009
Synonyms 9-chloro- 6-phenyl- 2-(2,2,2-trifluoroethyl)- 2,5-diazabicyclo[5.4.0] undeca- 5,8,10,12-tetraen -3-one
Chemical data
Formula C17H12ClF3N2O
Molar mass 352.7[[Script error: No such module "String".]]
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Halazepam is a benzodiazepine derivative and is marketed under the brand names Alapryl and Pacinone. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is a trifluoroethyl derivative of nordazepam.[1] While its structure may be similar to chlordiazepoxide and diazepam, it has both less toxicity and less tendency to cause paradoxical hostility and aggression than either of them.[2] Halazepam has active benzodiazepine metabolites.[3]


Halazepam is indicated for the treatment of anxiety.[4]

See also


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External links

pt:Halazepam sv:Halazepam
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  3. Jochemsen R, Breimer DD (1984). "Pharmacokinetics of benzodiazepines: metabolic pathways and plasma level profiles". Curr Med Res Opin. 8 Suppl 4: 60–79. PMID 6144464. 
  4. Lozano, Lozano, Lozano; et al. (1990). "[Open clinical study of the efficacy and safety of Halazepam in anxiety disorders]". Actas Luso Esp Neurol Psiquiatr Cienc Afines (in Spanish; Castilian). 18 (4): 205–11. PMID 1981637.