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Systematic (IUPAC) name
CAS Number 3258-51-3
ATC code none
PubChem CID 71122
Synonyms N-carbamoyl-5-methyl-2-oxo-3-prop-2-enyloxolane-3-carboxamide
Chemical data
Formula C10H14N2O4
Molar mass 226.229 g/mol[[Script error: No such module "String".]]
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Valofane is a sedative drug structurally related to the barbiturates[1] and similar drugs such as primidone. It is metabolised once inside the body to form the barbiturate proxibarbal and is thus a prodrug.[2]


  1. Traversa U, Puppini P, Jacquot C, Vertua R. Effect of an atypical barbiturate, the 2-allophanyl-2-allyl-4-valerolactone (valofan), on exploratory behaviour and brain serotonin concentrations in mice. Journal de Pharmacologie. 1985 Jul-Sep;16(3):279-90.
  2. Lambrey B, Compagnon PL, Jacquot C. Pharmacokinetics of 14C-2-allophanyl-2-allyl -gamma-valero-lactone: a prodrug of proxibarbal in rats. European Journal of Drug Metabolism and Pharmacokinetics. 1981;6(3):161-9.