Brallobarbital

Brallobarbital
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Systematic (IUPAC) name
	5-(2-bromoprop-2-en-1-yl)- 5-(prop-2-en-1-yl) pyrimidine- 2,4,6(1H,3H,5H)- trione
Identifiers
CAS Number	561-86-4
ATC code	none
PubChem	CID 68416
ChemSpider	61699
Synonyms	Brallobarbital
Chemical data
Formula	C10H11BrN2O3
Molar mass	287.110 g/mol[[Script error: No such module "String".]]
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Brallobarbital is a barbiturate derivative invented in 1964. It has sedative and hypnotic properties, and was used for the treatment of insomnia. Brallobarbital was primarily sold as part of a combination product called Vesparax, composed of 150 mg secobarbital, 50 mg brallobarbital and 50 mg hydroxyzine.^[1] The long half-life of this combination of drugs tended to cause a hangover effect the next day,^[2] and Vesparax fell into disuse once newer drugs with less side effects had been developed.^[3]

References

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fi:Brallobarbitaali

↑ Lhermann J. Clinical application of a new very active hypnotic associating sodium secobarbital, calcium brallobarbital and hydroxyzine (UC-8130). Gazette Medicale de France. 1964 Mar 10;71:961-2. (French)
↑ Yih TD, Rossum JM. Peculiar pharmacokinetics of brallobarbital as a source of complications in Vesparax intoxication. Xenobiotica. 1976 Jun;6(6):355-62.
↑ Fischbach R. Efficacy and safety of midazolam and vesparax in treatment of sleep disorders. British Journal of Clinical Pharmacology. 1983;16 Suppl 1:167S-171S.

[1] Lhermann J. Clinical application of a new very active hypnotic associating sodium secobarbital, calcium brallobarbital and hydroxyzine (UC-8130). Gazette Medicale de France. 1964 Mar 10;71:961-2. (French)

[2] Yih TD, Rossum JM. Peculiar pharmacokinetics of brallobarbital as a source of complications in Vesparax intoxication. Xenobiotica. 1976 Jun;6(6):355-62.

[3] Fischbach R. Efficacy and safety of midazolam and vesparax in treatment of sleep disorders. British Journal of Clinical Pharmacology. 1983;16 Suppl 1:167S-171S.

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Brallobarbital

References

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