Valofane
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Revision as of 00:51, 19 September 2010 by حسن علي البط (Talk) (Adding category Category:alkenes (using HotCat))
200px | |
Systematic (IUPAC) name | |
---|---|
3-allyl-N-(aminocarbonyl)-5-methyl-2-oxotetrahydrofuran-3-carboxamide | |
Identifiers | |
CAS Number | 3258-51-3 |
ATC code | none |
PubChem | CID 71122 |
Synonyms | N-carbamoyl-5-methyl-2-oxo-3-prop-2-enyloxolane-3-carboxamide |
Chemical data | |
Formula | C10H14N2O4 |
Molar mass | 226.229 g/mol[[Script error: No such module "String".]] |
Valofane is a sedative drug structurally related to the barbiturates[1] and similar drugs such as primidone. It is metabolised once inside the body to form the barbiturate proxibarbal and is thus a prodrug.[2]
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References
- ↑ Traversa U, Puppini P, Jacquot C, Vertua R. Effect of an atypical barbiturate, the 2-allophanyl-2-allyl-4-valerolactone (valofan), on exploratory behaviour and brain serotonin concentrations in mice. Journal de Pharmacologie. 1985 Jul-Sep;16(3):279-90.
- ↑ Lambrey B, Compagnon PL, Jacquot C. Pharmacokinetics of 14C-2-allophanyl-2-allyl -gamma-valero-lactone: a prodrug of proxibarbal in rats. European Journal of Drug Metabolism and Pharmacokinetics. 1981;6(3):161-9.
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