IC-26
From Self-sufficiency
| 200px | |
| Systematic (IUPAC) name | |
|---|---|
|
4-ethylsulfonyl-N,N-dimethyl-4,4-diphenylbutan-2-amine | |
| Identifiers | |
| PubChem | CID 113832 |
| Chemical data | |
| Formula | C20H27NO2S |
| Molar mass | 345.499[[Script error: No such module "String".]] |
| Script error: No such module "collapsible list". | |
IC-26 (WIN 1161-3, Methiodone) is an analogue of the opioid analgesic methadone, where the carbonyl group has been replaced by the bioisosteric sulfone group.
Human and animal studies suggest that IC-26 is around the same potency as methadone,[1][2] although other studies have found its activity to be inconsistent between different patients, with consistent opioid activity only being seen at a dose several times that of methadone. IC-26 was assessed for its abuse potential, but despite being found to have similar potential to methadone for development of dependence[3] it was never placed under international control as an illegal drug.
References
Cite error: Invalid <references> tag;
parameter "group" is allowed only.
<references />, or <references group="..." />
| 40px | This analgesic-related article is a stub. You can help ssf by expanding it. |
- ↑ Daniel Lednicer. Central Analgetics. (1982), p194. ISBN 0-471-08314-3
- ↑ Paul A J Janssen. Synthetic Analgesics Part 1: Diphenylpropylamines. Pergamon Press 1960. p161-163.
- ↑ Wolbach AB, Fraser HF. Addiction Liability of I-C-26. UNODC Bulletin on Narcotics 1963 Vol 1
Categories:
- Pages with script errors
- Pages with broken file links
- Infobox drug tracked parameters
- Chemical articles without CAS Registry Number
- Articles without EBI source
- Chemical pages without ChemSpiderID
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Articles without InChI source
- Articles without UNII source
- Drugboxes with an unspecified ATC code
- Drugs with no legal status
- Articles containing unverified chemical infoboxes
- Opioids
- Sulfonates
- Amines
- Analgesic stubs
- 2Fix
