Norcodeine

From Self-sufficiency

Norcodeine
Systematic (IUPAC) name
180px
3-methoxy- 6α-hydroxy- 4,5α-epoxy- 7,8-didehydromorphinan
Identifiers
CAS Number	467-15-2
ATC code	none
PubChem	CID 1255
Chemical data
Formula	C₁₇H₁₉NO₃
Molar mass	285.337 g/mol[[Script error: No such module "String".]]

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Norcodeine is an opiate analogue that is the N-demethylated derivative of codeine.

Norcodeine has relatively little opioid activity in its own right,^[1] but is formed as a metabolite of codeine following ingestion.^[2]

References

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Opioids (N02A)

Opium and
Poppy straw
derivatives

Crude opiate extracts/
whole opium products

Compote/Kompot/Polish heroin · Diascordium · B & O Supprettes · Dover's powder · Laudanum · Mithridate · Opium · Paregoric · Poppy straw concentrate · Poppy tea · Smoking opium · Theriac

Natural Opiates

Opium Alkaloids see also: Components of Opium	Codeine · Morphine · Oripavine · Pseudomorphine · Thebaine
Alkaloid Salts Mixtures	Pantopon · Papaveretum (Omnopon) · Tetrapon

Semisynthetics

Morphine Family	2-(p-Nitrophenyl)-4-isopropylmorphine · 14-Hydroxymorphine · 14β-Hydroxymorphine · 14β-Hydroxymorphone · 2,4-Dinitrophenylmorphine · 6-Methyldihydromorphine · 6-Methylenedihydrodesoxymorphine · 6-Acetyldihydromorphine/6-Monoacetyldihydromorphine · Acetyldihydromorphine · Azidomorphine · Chlornaltrexamine · Dihydrodesoxymorphine (Desomorphine) · Dihydromorphine · Ethyldihydromorphine · Hydromorphinol · Methyldesorphine · N-Phenethylnormorphine · Pseudomorphine · RAM-378
3,6 Diesters of Morphine	6-acetyl-1-iodocodeine · 6-nicotinoyldihydromorphine · Acetylpropionylmorphine · Acetylbutyrylmorphine · Diacetyldihydromorphine (Dihydroheroin) · Diacetyldibenzoylmorphine · Dibutyrylcodeine · Dibutyrylmorphine · Dibenzoylmorphine · Diformylmorphine · Dipropanoylmorphine · Heroin (Diacetylmorphine) · Nicomorphine · Tetrabenzoylmorphine · Tetrabutyrylmorphine
Codeine-Dionine Family	14-Hydroxydihydrocodeine · Acetylcodeine · Benzylmorphine · Codeine methylbromide · Desocodeine · Dimethylmorphine (Methocodeine) · Methyldihydromorphine (Dihydroheterocodeine) · Ethylmorphine (Dionine) · Heterocodeine · Isocodeine · Isopropylmorphine · Morpholinylethylmorphine (Pholcodine) · Myrophine · Nalodeine · Transisocodeine
Morphinones & Morphols	1-Bromohydrocodone · 1-Bromooxycodone · 1-Chlorohydrocodone · 1-Chlorooxycodone · 1-Iodohydrocodone · 1-Iodooxycodone · 14-Cinnamoyloxycodeinone · 14-Ethoxymetopon · 14-Methoxymetopon · 14β-Hydroxymorphone · 14-O-Methyloxymorphone · 14-Phenylpropoxymetopon · 7-Spiroindanyloxymorphone · 8,14-Dihydroxydihydromorphinone · Acetylmorphinol · Acetylmorphone · α-hydrocodol · Bromoisopropropyldihydromorphinone · Codeinone · Codorphone · Codol · Codoxime · Thebacon (Acetyldihydrocodeinone / Dihydrocodeinone enol acetate) · Ethyldihydromorphinone · Hydrocodol · Hydrocodone · Hydromorphinone · Hydromorphol · Hydromorphone · Hydroxycodeine · Isopropropyldihydrocodeinone · Isopropropyldihydromorphinone · Methyldihydromorphinone · Metopon · Morphenol · Morphinol · Morphinone · Morphol · N-Phenethyl-14-ethoxymetopon · Oxycodone · Oxymorphol · Oxymorphinol · Oxymorphone · Pentamorphone · Semorphone
Morphides	α-chlorocodide (Alphachlorocodide/Chlorocodide) · α-chloromorphide · 3-Bromomorphide · Bromocodide · Bromomorphide (8-Bromomorphide) · Chlorocodide · Chloromorphide · · Codide · Fluorocodide (8-Fluorocodide) · Fluormorphide · Iodocodide · Iodomorphide (8-Iodomorphide) · Morphide
Dihydrocodeine Series	14-hydroxydihydrocodeine · Acetyldihydrocodeine · Dihydrocodeine · Dihydrodesoxycodeine/Desocodeine · Dihydroisocodeine · Nicocodeine · Nicodicodeine
Nitrogen Morphine Derivatives	1-Nitrocodeine · 2-Nitrocodeine · 1-Nitromorphine · 2-Nitromorphine · Codeine-N-Oxide · Heroin-N-Oxide · Hydromorphone-N-Oxide · Morphine-N-Oxide
Hydrazones	Acetylmorphazone · Hydromorphazone · Morphazone · Oxymorphazone
Halogenated Morphine Derivatives	1-Bromocodeine · 2-Bromocodeine · 1-Bromodiacetylmorphine · 2-Bromodiacetylmorphine · 1-Bromodihydrocodeine · 2-Bromodihydrocodeine · 1-Bromodihydromorphine · 2-Bromodihydromorphine · 1-Bromomorphine · 2-Bromomorphine · 1-Chlorocodeine · 2-Chlorocodeine · 1-Chlorodiacetylmorphine · 2-Chlorodiacetylmorphine · 1-Chlorodihydrocodeine · 2-Chlorodihydrocodeine · 1-Chlorodihydromorphine · 2-Chlorodihydromorphine · 1-Chloromorphine · 2-Chloromorphine · 1-Fluorocodeine · 2-Fluorocodeine · 1-Fluorodiacetylmorphine · 2-Fluorodiacetylmorphine · 1-Fluorodihydrocodeine · 2-Fluorodihydrocodeine · 1-Fluorodihydromorphine · 2-Fluorodihydromorphine · 1-Fluoromorphine · 2-Fluoromorphine · 3-Fluoromorphine · 1-Iodocodeine · 2-Iodocodeine · 1-Iododiacetylmorphine · 2-Iododiacetylmorphine · 1-Iododihydrocodeine · 2-Iododihydrocodeine · 1-Iododihydromorphine · 2-Iododihydromorphine · 1-Iodomorphine · 2-Iodomorphine · Chlorethylmorphine
Others	Pholcodine

Active Opiate
Metabolites

Codeine-N-Oxide (Genocodeine) · Dihydromorphine-6-glucuronide · Hydromorphone-N-Oxide · Heroin-7,8-Oxide · Morphine-6-glucuronide · 6-Acetylmorphine · Morphine-N-Oxide (Genomorphine) · Naltrexol · Norcodeine · Normorphine

Morphinans

Morphinan Series	4-chlorophenylpyridomorphinan · Cyclorphan · Dextrallorphan · Dimemorfan · Levargorphan · Levallorphan · Levorphanol · Levorphan · Levophenacylmorphan · Levomethorphan · Norlevorphanol · N-Methylmorphinan · Oxilorphan · Phenomorphan · Methorphan / Racemethorphan · Morphanol / Racemorphanol · Ro4-1539 · Stephodeline · Xorphanol
Others	1-Nitroaknadinine · 14-episinomenine · 5,6-Dihydronorsalutaridine · 6-Ketonalbuphine · Aknadinine · Butorphanol · Cephakicine · Cephasamine · Cyprodime · Drotebanol · Fenfangjine G · Nalbuphine · Sinococuline · Sinomenine (Cocculine) · Tannagine

Benzomorphans

5,9-DEHB · Alazocine · Anazocine · Bremazocine · Cogazocine · Cyclazocine · Dezocine · Eptazocine · Etazocine · Ethylketocyclazocine · Fluorophen · Ketazocine · Metazocine · Pentazocine · Phenazocine · Quadazocine · Thiazocine · Tonazocine · Volazocine · Zenazocine

4-Phenylpiperidines

Pethidines (Meperidines)	4-Fluoromeperidine · Allylnorpethidine · Anileridine · Benzethidine · Carperidine · Difenoxin · Diphenoxylate · Etoxeridine (Carbetidine) · Furethidine · Hydroxypethidine (Bemidone) · Hydroxymethoxypethidine · Morpheridine · Oxpheneridine (Carbamethidine) · Meperidine-N-Oxide · Pethidine (Meperidine) · Pethidine Intermediate A · Pethidine Intermediate B (Norpethidine) · Pethidine Intermediate C (Pethidinic Acid) · Pheneridine · Phenoperidine · Piminodine · Properidine (Ipropethidine) · Sameridine
Prodines	Allylprodine · Isopromedol · Meprodine (α-meprodine / β-meprodine) · MPPP (Desmethylprodine) · PEPAP · Prodine (α-prodine / β-prodine) · Prosidol · Trimeperidine (Promedol)
Ketobemidones	Acetoxyketobemidone · Droxypropine · Ketobemidone · Methylketobemidone · Propylketobemidone
Others	Alvimopan · Loperamide · Picenadol

Open Chain
Opioids

Amidones	Dextromethadone · Dextroisomethadone · Dipipanone · Hexalgon (Norpipanone) · Isomethadone · Levoisomethadone · Levomethadone · Methadone · Methadone intermediate · Normethadone · Norpipanone · Phenadoxone (Heptazone) · Pipidone
Methadols	Dimepheptanol (Racemethadol) · Levacetylmethadol · Noracetylmethadol
Moramides	Dextromoramide · Levomoramide · Moramide intermediate · Racemoramide
Thiambutenes	Diethylthiambutene · Dimethylthiambutene · Ethylmethylthiambutene · Piperidylthiambutene · Pyrrolidinylthiambutene · Thiambutene · Tipepidine
Phenalkoxams	Dextropropoxyphene (Propoxyphene) · Dimenoxadol · Dioxaphetyl Butyrate · Levopropoxyphene · Norpropoxyphene
Ampromides	Diampromide · Phenampromide · Propiram
Others	IC-26 · Isoaminile · Lefetamine · R-4066

Anilidopiperidines

3-Allylfentanyl · 3-Methylfentanyl · 3-Methylthiofentanyl · 4-Phenylfentanyl · Alfentanil · α-methylacetylfentanyl · α-methylfentanyl · α-methylthiofentanyl · Benzylfentanyl · β-hydroxyfentanyl · β-hydroxythiofentanyl · β-methylfentanyl · Brifentanil · Carfentanil · Fentanyl · Lofentanil · Mirfentanil · Ocfentanil · Ohmefentanyl · Parafluorofentanyl · Phenaridine · Remifentanil · Sufentanil · Thenylfentanyl · Thiofentanyl · Trefentanil

Oripavine
derivatives

6,14-Endoethenotetrahydrooripavine · 7-PET · Acetorphine · Alletorphine · BU-48 · Buprenorphine · Butorphine · Cyprenorphine · Dihydroetorphine · Diprenorphine (M5050) · Etorphine · 18,19-Dehydrobuprenorphine (HS-599) · N-cyclopropylmethyl-noretorphine · Nepenthone · Norbuprenorphine · Thevinone · Thienorphine

Phenazepanes

Ethoheptazine · Meptazinol · Metheptazine · Metethoheptazine · Proheptazine

Pirinitramides

Bezitramide · Piritramide

Benzimidazoles

Clonitazene · Etonitazene · Nitazene

Indoles

18-MC · 7-Acetoxymitragynine · 7-Hydroxymitragynine · Akuammidine · Akuammine · Eseroline · Hodgkinsine · Ibogaine · Mitragynine · Noribogaine · Pericine · ψ-Akuammigine

Diphenylmethylpiperazines

BW373U86 · DPI-221 · DPI-287 · DPI-3290 · SNC-80

Opioid peptides
see also: The Opioid Peptides

Adrenorphin · Amidorphin · Casomorphin · DADLE · DALDA · DAMGO · Dermenkephalin · Dermorphin · Deltorphin · DPDPE · Dynorphin · Endomorphin · Endorphin · Enkephalin · Gliadorphin · Morphiceptin · Nociceptin · Octreotide · Opiorphin · Rubiscolin · TRIMU 5

Others

3-(3-Methoxyphenyl)-3-ethoxycarbonyltropane · AH-7921 • Azaprocin · BDPC · Bisnortilidine · BRL-52537 · Bromadoline • C-8813 · Ciramadol · Doxpicomine • Enadoline · Esketamine · Faxeladol · GR-89696 · Herkinorin · ICI-199,441 · ICI-204,448 · J-113,397 · JTC-801 · Ketamine · LPK-26 · Methopholine · Methoxetamine · N-Desmethylclozapine · NNC 63-0532 · Nortilidine · O-Desmethyltramadol · Phenadone · Phencyclidine · Prodilidine · Profadol · Ro64-6198 · Salvinorin A · SB-612,111 · SC-17599 · RWJ-394,674 · TAN-67 · Tapentadol · Tecodine · Tifluadom · Tilidine · Tramadol · Trimebutine · U-50,488 · U-69,593 · Viminol · W-18 ·

Opioid Antagonists
&
Inverse-Agonists

5'-Guanidinonaltrindole · β-Funaltrexamine · 6β-Naltrexol · Alvimopan · Amiphenazole · Binaltorphimine · Chlornaltrexamine · Clocinnamox · Cyclazocine · Cyprodime · Diprenorphine (M5050) · Fedotozine · JDTic · Levallorphan · Methocinnamox · Methylnaltrexone · Nalfurafine · Nalmefene · Nalmexone · Naloxazone · Naloxonazine · Naloxone · Naloxone benzoylhydrazone · Nalorphine · Naltrexone · Naltriben · Naltrindole · Norbinaltorphimine · Oxilorphan · S-allyl-3-hydroxy-17-thioniamorphinan (SAHTM)

ru:Норкодеин

↑ Fraser HF, Isbell H, Van Horn GD. Human pharmacology and addiction liability of norcodeine. Journal of Pharmacology and Experimental Therapeutics. 1960 Jun;129:172-7. PMID 13824628
↑ Posey BL, Kimble SN. High-performance liquid chromatographic study of codeine, norcodeine, and morphine as indicators of codeine ingestion. Journal of Analytical Toxicology. 1984 Mar-Apr;8(2):68-74. PMID 6716978.

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Norcodeine

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