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|Molar mass||366.497 g/mol[[Script error: No such module "String".]]|
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Ohmefentanyl is one of the most potent μ-receptor agonists known, comparable to super-potent opioids such as carfentanil and etorphine which are used for tranquilizing large animals such as elephants in veterinary medicine. In mouse studies, the most active isomer 3R,4S,βS-ohmefentanyl was 28 times more powerful as a painkiller than fentanyl, the chemical from which it is derived, and 6300 times more effective than morphine.. Ohmefentanyl has three stereogenic centers and so has eight stereoisomers, which are named F9201-F9208. Researchers are studying the different pharmaceutical properties of these isomers..
- Guo, GW; He, Y; Jin, WQ; Zou, Y; Zhu, YC; Chi, ZQ (2000). "Comparison of physical dependence of ohmefentanyl stereoisomers in mice". Life sciences. 67 (2): 113–20. doi:10.1016/S0024-3205(00)00617-2. PMID 10901279.
- Liu, Z.; He, Y.; Jin, W.; Chen, X.; Shen, Q.; Chi, Z. (2004). "Effect of chronic treatment of ohmefentanyl stereoisomers on cyclic AMP formation in Sf9 insect cells expressing human mu-opioid receptors". Life sciences. 74 (24): 3001–3008. doi:10.1016/j.lfs.2003.10.027. PMID 15051423.
- Yong, Z; Hao, W; Weifang, Y; Qiyuan, D; Xinjian, C; Wenqiao, J; Youcheng, Z (2003). "Synthesis and analgesic activity of stereoisomers of cis-fluoro-ohmefentanyl". Die Pharmazie. 58 (5): 300–2. PMID 12779044.
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