Fluprazine
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| File:Fluprazine.png | |
| Systematic (IUPAC) name | |
|---|---|
|
2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethylurea | |
| Clinical data | |
| Routes of administration | Oral |
| Legal status | |
| Legal status |
|
| Identifiers | |
| CAS Number | 76716-60-4 |
| ATC code | none |
| PubChem | CID 71153 |
| ChemSpider | 64297 |
| Chemical data | |
| Formula | C14H19F3N4O |
| Molar mass | 316.151 g/mol[[Script error: No such module "String".]] |
| Script error: No such module "collapsible list". | |
Fluprazine (DU-27,716) is a drug of the phenylpiperazine class. It is a so-called serenic or antiaggressive agent.[1] It is closely related to several other piperazines, including eltoprazine and batoprazine, and TFMPP, as well as more distantly to the azapirones such as buspirone. The pharmacology of fluprazine is unknown, but it is likely to act as an agonist at the 5-HT1A and 5-HT1B receptors like its sister compound eltoprazine.
See also
References
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Serenics (Antiaggressive Agents) | |
|---|---|
| Serotonin Reuptake Inhibitors | |
| Serotonin Releasing Agents | |
| Monoamine Oxidase Inhibitors | |
| Serotonin Synthesis Precursors | |
| 5-HT1A Receptor Agonists | 8-OH-DPAT • Batoprazine • Buspirone • Eltoprazine • Fluprazine • Gepirone • Ipsapirone • S-15535 • Tandospirone • ..... |
| 5-HT1B Receptor Agonists | Batoprazine • Eltoprazine • Fluprazine • ..... |
| Oxytocin Receptor Agonists | |
| Miscellaneous | Antiandrogens • Atypical Antipsychotics • Benzodiazepines • Beta Blockers • Clonidine • Lithium • Medetomidine • ..... |
| Simple piperazines (no additional rings) | |
|---|---|
| Phenylpiperazines | Acaprazine • Antrafenine • Aripiprazole • Batoprazine • Bifeprunox • BRL-15,572 • Ciprofloxacin • CSP-2503 • Dapiprazole • DCPP • DMPP • Dropropizine • EGIS-12,233 • Elopiprazole • Eltoprazine • Enpiprazole • Ensaculin • Etoperidone • Flesinoxan • Flibanserin • Fluprazine • Itraconazole • Ketoconazole • Levodropropizine • Lorpiprazole • mCPP • MeOPP • Mepiprazole • Naftopidil • Naphthylpiperazine • Nefazodone • Niaprazine • Oxypertine • Pardoprunox • pCPP • pFPP • Posaconazole • PRX-00023 • S-14,506 • S-14,671 • S-15,535 • SB-258,585 • SB-271,046 • SB-357,134 • SB-399,885 • Sonepiprazole • TFMPP • Tolpiprazole • Trazodone • Urapidil • Vesnarinone • Vilazodone • WAY-100,135 • WAY-100,635 |
| Benzylpiperazines | 2C-B-BZP • Befuraline • Bifeprunox • Buclizine • BZP • Chlorbenzoxamine • DBZP • Fipexide • Imatinib • MBZP • MDBZP • Meclozine • Piberaline • Piribedil • Trimetazidine • Vesnarinone |
| Diphenylalkylpiperazines (benzhydrylalkylpiperazines) | Almitrine • Amperozide • BRL-15,572 • Buclizine • BW373U86 • Cetirizine • Chlorbenzoxamine • Chlorcyclizine • Cinnarizine • Clocinizine • Cyclizine • DBL-583 • Diphenylmethylpiperazine • Dotarizine • DPI-221 • DPI-287 • DPI-3290 • GBR-12,783 • GBR-12,935 • GBR-13,069 • GBR-13,098 • GBR-13,119 • Hydroxyzine • Lidoflazine • Manidipine • Meclozine • Oxatomide • SNC-80 • Vanoxerine |
| Pyrimidinylpiperazines | Buspirone • Dasatinib • Eptapirone • Gepirone • Ipsapirone • Piribedil • Pyrimidinylpiperazine • Revospirone • Tandospirone • Tirilazad • Trimazosin • Umespirone • Zalospirone |
| Pyridinylpiperazines | |
| Benzo(iso)thiazolylpiperazines | |
| Tricyclics (piperazine attached via side chain) | |
| Others | 6-Nitroquipazine • Azimilide • Cinepazet • Cyclohexylpiperazine • Hexocyclium • Indinavir • JNJ-7777120 • Lodenafil • Mirodenafil • PB-28 • Quipazine • Ranolazine • SA-4503 • Sildenafil • Tadalafil • Vardenafil • VUF-6002 • Zipeprol |
- ↑ van der Poel AM, Olivier B, Mos J, Kruk MR, Meelis W, van Aken JH. (1982). "Anti-aggressive effect of a new phenylpiperazine compound (DU27716) on hypothalamically induced behavioural activities". Pharmacol Biochem Behav. 17 (1): 147–153. doi:10.1016/0091-3057(82)90277-5. PMID 6889746. CS1 maint: Multiple names: authors list (link)
Retrieved from "http://ssf.f15ijp.com/wiki/index.php?title=Fluprazine&oldid=23759"
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