4-Phenylfentanyl
| 240px | |
| Systematic (IUPAC) name | |
|---|---|
|
N-(1-phenethyl-4-phenyl-4-piperidyl)-N-phenyl-propanamide | |
| Identifiers | |
| ATC code | none |
| PubChem | CID 10319503 |
| Synonyms | 4-Phenylfentanyl |
| Chemical data | |
| Formula | C28H32N2O |
| Molar mass | 412.565 g/mol[[Script error: No such module "String".]] |
| Script error: No such module "collapsible list". | |
4-Phenylfentanyl is an opioid analgesic that is a derivative of fentanyl. It was developed during the course of research that ultimately resulted in super-potent opioid derivatives such as carfentanil, though it is a substantially less potent analogue. 4-Phenylfentanyl is around 8x the potency of fentanyl in analgesic tests on animals, but more complex 4-heteroaryl derivatives such as substituted thiophenes and thiazoles are more potent still, as they are closer bioisosteres to the 4-carbomethoxy group of carfentanil.[1]
Side effects of fentanyl analogues are similar to those of fentanyl, and include itching, nausea and potentially serious respiratory depression which can be life-threatening.
References
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