Nalfurafine
From Self-sufficiency
| File:Nalfurafine.svg | |
| Systematic (IUPAC) name | |
|---|---|
|
(2E)-N-[(5α,6β)-17-(cyclopropylmethyl)- 3,14-dihydroxy- 4,5-epoxymorphinan- 6-yl]- 3-(3-furyl)- N-methylacrylamide | |
| Clinical data | |
| Routes of administration | intravenous |
| Identifiers | |
| CAS Number | 152658-17-8 |
| ATC code | V03AX02 (WHO) |
| PubChem | CID 6445230 |
| IUPHAR/BPS | 1651 |
| Synonyms | TRK-820 |
| Chemical data | |
| Formula | C28H32N2O5 |
| Molar mass | 476.564 g/mol[[Script error: No such module "String".]] |
Nalfurafine (INN and USAN;[1] also known as AC-820, TRK-820; trade name Remitch) is a κ-opioid receptor agonist marketed as a treatment for uremic pruritus in people undergoing hemodialysis.[2]
As of January 2010[update], it is also being investigated for the treatment of pruritus in patients with chronic liver disease.[3]
References
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