DADLE
From Self-sufficiency
| DADLE | |
|---|---|
| File:2-D-Alanine-5-D-leucine-enkephalin.png | |
| (2R)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid | |
| Other names • [D-Ala2, D-Leu5]-Enkephalin • L-Tyrosyl-D-alanylglycyl-L-phenylalanyl-D-Leucine • N-(N-(N-(N-L-tyrosyl-D-alanyl)glycyl)-L-phenylalanyl)-D-Leucine • Tyr-D-Ala-Gly-Phe-D-Leu-OH | |
| style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers | |
| CAS number | 63631-40-3 |
| PubChem | 6917707 |
| SMILES | Script error: No such module "collapsible list". |
| style="background: #F8EABA; text-align: center;" colspan="2" | Properties | |
| Molecular formula | C29H39N5O7 |
| Molar mass | 569.65 g mol−1 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) | |
| Infobox references | |
DADLE ([D-Ala2, D-Leu5]-Enkephalin) is a synthetic opioid peptide with analgesic properties. Although it is often considered a selective delta opioid receptor agonist, it also binds to the μ1 subtype of mu opioid receptors.
Treatment with DADLE results in transient depression of mean arterial blood pressure and heart rate.[1][2]
Its peptide sequence is Tyr-D-Ala-Gly-Phe-D-Leu.
References
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