Pethidine intermediate A

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Pethidine intermediate A
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Systematic (IUPAC) name
1-methyl-4-phenylpiperidine-4-carbonitrile
Clinical data
Routes of
administration
N/A
Legal status
Legal status
Identifiers
CAS Number 3627-62-1
ATC code none
PubChem CID 62513
Chemical data
Formula C13H16N2
Molar mass 200.28 g/mol[[Script error: No such module "String".]]
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Pethidine intermediate A is a 4-phenylpiperidine derivative that is a precursor to the opioid analgesic drug pethidine (meperidine). It is not known to have any analgesic activity in its own right, however other derivatives of pethidine with a 4-cyano group in place of the carboxylate ethyl ester have been found to be active,[1] so pethidine intermediate A might also show opioid effects.

See also

References

  1. Lomenzo SA, Rhoden JB, Izenwasser S, Wade D, Kopajtic T, Katz JL, Trudell ML. Synthesis and Biological Evaluation of Meperidine Analogues at Monoamine Transporters. Journal of Medicinal Chemistry. 2005; 48:1336-1343.