Pethidine intermediate A
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Revision as of 08:09, 29 August 2010 by حسن علي البط (Talk) (Removed Category:Alkynes; Adding category Category:Nitriles (using HotCat))
| 160px | |
| Systematic (IUPAC) name | |
|---|---|
|
1-methyl-4-phenylpiperidine-4-carbonitrile | |
| Clinical data | |
| Routes of administration | N/A |
| Legal status | |
| Legal status |
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| Identifiers | |
| CAS Number | 3627-62-1 |
| ATC code | none |
| PubChem | CID 62513 |
| Chemical data | |
| Formula | C13H16N2 |
| Molar mass | 200.28 g/mol[[Script error: No such module "String".]] |
Pethidine intermediate A is a 4-phenylpiperidine derivative that is a precursor to the opioid analgesic drug pethidine (meperidine). It is not known to have any analgesic activity in its own right, however other derivatives of pethidine with a 4-cyano group in place of the carboxylate ethyl ester have been found to be active,[1] so pethidine intermediate A might also show opioid effects.
See also
References
- ↑ Lomenzo SA, Rhoden JB, Izenwasser S, Wade D, Kopajtic T, Katz JL, Trudell ML. Synthesis and Biological Evaluation of Meperidine Analogues at Monoamine Transporters. Journal of Medicinal Chemistry. 2005; 48:1336-1343.
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