Brallobarbital

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Brallobarbital
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Systematic (IUPAC) name
5-(2-bromoprop-2-en-1-yl)- 5-(prop-2-en-1-yl) pyrimidine- 2,4,6(1H,3H,5H)- trione
Identifiers
CAS Number 561-86-4
ATC code none
PubChem CID 68416
ChemSpider 61699
Synonyms Brallobarbital
Chemical data
Formula C10H11BrN2O3
Molar mass 287.110 g/mol[[Script error: No such module "String".]]
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Brallobarbital is a barbiturate derivative invented in 1964. It has sedative and hypnotic properties, and was used for the treatment of insomnia. Brallobarbital was primarily sold as part of a combination product called Vesparax, composed of 150 mg secobarbital, 50 mg brallobarbital and 50 mg hydroxyzine.[1] The long half-life of this combination of drugs tended to cause a hangover effect the next day,[2] and Vesparax fell into disuse once newer drugs with less side effects had been developed.[3]

References

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40x30px This sedative-related article is a stub. You can help ssf by expanding it.
GABAA receptor
Ultrashort-acting
Short/intermediate-
acting
Long-acting
Ungrouped
Short-acting
Intermediate-acting
Long-acting
Dialkylphenols
Alpha-2 adrenergic
receptor
Melatonin receptor
Histamine receptor &
Acetylcholine receptor
5-HT2A &
α1-adrenergic
Selective 5-HT2A & α1-adrenergic antagonists
GABAB receptor /
GHB receptor
GHB Type
Orexin receptors
Orexin antagonists
Other receptors/
ungrouped
Other

M: PSO/PSI

dsrd (o, p, m, p, a, d, s), sysi/epon, spvo

proc, drug(N5A/5B/5C/6A/6B/6D)

fi:Brallobarbitaali
  1. ↑ Lhermann J. Clinical application of a new very active hypnotic associating sodium secobarbital, calcium brallobarbital and hydroxyzine (UC-8130). Gazette Medicale de France. 1964 Mar 10;71:961-2. (French)
  2. ↑ Yih TD, Rossum JM. Peculiar pharmacokinetics of brallobarbital as a source of complications in Vesparax intoxication. Xenobiotica. 1976 Jun;6(6):355-62.
  3. ↑ Fischbach R. Efficacy and safety of midazolam and vesparax in treatment of sleep disorders. British Journal of Clinical Pharmacology. 1983;16 Suppl 1:167S-171S.
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