Dimemorfan

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Dimemorfan
File:Dimemorfan.png
Systematic (IUPAC) name
(9α,13α,14α)-3,17-dimethylmorphinan
Identifiers
CAS Number 36309-01-0
ATC code R05DA11 (WHO)
PubChem CID 3037918
Chemical data
Formula C18H25N
Molar mass 255.398 g/mol[[Script error: No such module "String".]]
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Dimemorfan is an antitussive or cough suppressant which acts as a sigma receptor agonist.[1][2] It is an analogue of dextromethorphan and dextrorphan, but lacks significant NMDA receptor antagonistic action and dissociative effects, thereby having reduced abuse potential and adverse effects in comparison.[3]

See also

References

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Expectorants
Mucolytics
Cough suppressants
Opium alkaloids,
opioids,
and derivatives
Other

M: RES

anat(n, x, l, c)/phys/devp

proc, drug(R1/2/3/5/6/7)


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  1. ↑ Hui-Hung Wang, Jyh-Wei Chien, Yueh-Ching Chou, Jyh-Fei Liao and Chieh-Fu Chen. Anti-amnesic effect of dimemorfan in mice. British Journal of Pharmacology (2003) 138, 941–949.
  2. ↑ Eun-Joo Shin, Seung-Yeol Nah, Won-Ki Kim, Kwang Ho Ko, Wang-Kee Jhoo, Yong-Kwang Lim, Joo Young Cha, Chieh-Fu Chen and Hyoung-Chun Kim. The dextromethorphan analog dimemorfan attenuates kainate-induced seizures via sigma1 receptor activation: comparison with the effects of dextromethorphan. British Journal of Pharmacology (2005) 144, 908–918.
  3. ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
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