Dimemorfan
From Self-sufficiency
| File:Dimemorfan.png | |
| Systematic (IUPAC) name | |
|---|---|
|
(9α,13α,14α)-3,17-dimethylmorphinan | |
| Identifiers | |
| CAS Number | 36309-01-0 |
| ATC code | R05DA11 (WHO) |
| PubChem | CID 3037918 |
| Chemical data | |
| Formula | C18H25N |
| Molar mass | 255.398 g/mol[[Script error: No such module "String".]] |
Dimemorfan is an antitussive or cough suppressant which acts as a sigma receptor agonist.[1][2] It is an analogue of dextromethorphan and dextrorphan, but lacks significant NMDA receptor antagonistic action and dissociative effects, thereby having reduced abuse potential and adverse effects in comparison.[3]
See also
References
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- ↑ Hui-Hung Wang, Jyh-Wei Chien, Yueh-Ching Chou, Jyh-Fei Liao and Chieh-Fu Chen. Anti-amnesic effect of dimemorfan in mice. British Journal of Pharmacology (2003) 138, 941–949.
- ↑ Eun-Joo Shin, Seung-Yeol Nah, Won-Ki Kim, Kwang Ho Ko, Wang-Kee Jhoo, Yong-Kwang Lim, Joo Young Cha, Chieh-Fu Chen and Hyoung-Chun Kim. The dextromethorphan analog dimemorfan attenuates kainate-induced seizures via sigma1 receptor activation: comparison with the effects of dextromethorphan. British Journal of Pharmacology (2005) 144, 908–918.
- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
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