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Systematic (IUPAC) name
Legal status
Legal status
  • Uncontrolled
Pharmacokinetic data
Biological half-life ~12 hours
CAS Number 935-07-9
ATC code none
PubChem CID 6537404
ChemSpider 5020586
Chemical data
Formula C8H10N2
Molar mass 134.18 g/mol[[Script error: No such module "String".]]
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Phenylethylidenehydrazine (PEH) is an inhibitor of the enzyme GABA transaminase (GABA-T).[1][2] It is a metabolite of the antidepressant phenelzine and is responsible for its elevation of GABA concentrations.[1] PEH likely plays a significant role in phenelzine's high efficacy in treating anxiety disorders.

See also


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  2. Duffy S, Nguyen PV, Baker GB (2004). "Phenylethylidenehydrazine, a novel GABA-transaminase inhibitor, reduces epileptiform activity in rat hippocampal slices". Neuroscience. 126 (2): 423–32. doi:10.1016/j.neuroscience.2004.03.007. PMID 15207360.