Iproclozide

Iproclozide
	File:Iproclozide .svg
Systematic (IUPAC) name
	2-(4-chlorophenoxy)-N'-isopropyl-acetohydrazide
Clinical data
Routes of; administration	Oral
Legal status
Legal status	Uncontrolled;
Identifiers
CAS Number	3544-35-2
ATC code	N06AF06 (WHO)
PubChem	CID 19063
ChemSpider	17998
Chemical data
Formula	C11H15ClN2O2
Molar mass	242.70 g/mol[[Script error: No such module "String".]]

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Iproclozide (trade names Sursum, Sinderesin) is an irreversible and selective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was used as an antidepressant, but has since been discontinued.^[1] It has been known to cause fulminant hepatitis and there have been at least three reported fatalities due to administration of the drug.^[2]^[3]

References

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↑ Suerinck A, Suerinck E. (1966). "[Depressive states in a sanatorium milieu and monoamine oxidase inhibitors. (Therapeutic results by the combination of iproclozide and chlordiazepoxide). Apropos of 146 cases]". J Med Lyon. 47 (96): 573–586. PMID 5930723.
↑ Pessayre D, de Saint-Louvent P, Degott C, Bernuau J, Rueff B, Benhamou JP. (1978). "Iproclozide fulminant hepatitis. Possible role of enzyme induction". Gastroenterology. 75 (3): 492–496. PMID 680506.
↑ Neil Kaplowitz, Laurie D. DeLeve (2003). Drug-induced liver disease. Informa Health Care. p. 455. ISBN 0824708113, 9780824708115 Check |isbn= value: invalid character (help). More than one of |pages= and |page= specified (help)