Nafadotride

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Nafadotride
File:Nafadotride.svg
style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers
CAS number 149649-22-9
PubChem 3408722
MeSH Nafadotride
IUPHAR ligand 44
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style="background: #F8EABA; text-align: center;" colspan="2" | Properties
Molecular formula C22H27N3O2
Molar mass 365.47 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Nafadotride is a dopamine antagonist with reasonable selectivity for the D3 subtype (9.6 times selectivity for D3 over D2).[1]

References

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  1. Pilla M, Perachon S, Sautel F, Garrido F, Mann A, Wermuth CG, Schwartz JC, Everitt BJ, Sokoloff P. Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 agonist. Nature. 1999;400:371–375.