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Fezolamine (Win-41,528-2) is a drug which was investigated as an antidepressant in the 1980s. It acts as a serotonin, norepinephrine, and dopamine reuptake inhibitor, with 3- to 4-fold preference for the former neurotransmitter. It was found to be effective and well-tolerated in clinical trials but was never marketed.
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- ↑ 2.0 2.1 Zisook S, Mendels J, Janowsky D, Feighner J, Lee JC, Fritz A (1987). "Efficacy and safety of fezolamine in depressed patients". Neuropsychobiology. 17 (3): 133–8. PMID 3683802.