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File:CX157 structure.svg
Systematic (IUPAC) name
3-fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiine 10,10-dioxide
Clinical data
Routes of
Legal status
Legal status
  • Uncontrolled
ATC code none
PubChem CID 18687754
ChemSpider 13701383
Chemical data
Formula C14H8F4O4S
Molar mass 348.27 g/mol
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Tyrima (CX157) is a selective and reversible inhibitor of MAO-A (RIMA).[1] It is currently in phase II clinical trials for the treatment of depression.[2]

See also


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  1. Fielding R, Mielach F, Free J, Pande A (2007). "Pharmacokinetics and oral bioavailability of CX157, a reversible selective MAO-A inhibitor, in primates". 2007 AAPS Annual Meeting & Exposition. http://www.aapsj.org/abstracts/AM_2007/AAPS2007-001233.PDF. Retrieved 2009-06-14. 
  2. ClinicalTrials.gov NCT00739908