Benperidol

From Self-sufficiency
Jump to: navigation, search
Benperidol
250px
Systematic (IUPAC) name
1-{1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one
Clinical data
Routes of
administration
Oral
Legal status
Legal status
Identifiers
CAS Number 983-42-6
ATC code N05AD07 (WHO)
PubChem CID 16363
ChemSpider 15521
Chemical data
Formula C22H24FN3O2
Molar mass 381.443 g/mol[[Script error: No such module "String".]]
Script error: No such module "collapsible list".
  (verify)
Script error: No such module "TemplatePar".Expression error: Unexpected < operator.

Benperidol is a drug which is a highly potent butyrophenone derivative. It is in fact the most potent neuroleptic on the European market, with chlorpromazine equivalency as high as 75 to 100 (about 150 to 200% potency in terms of dose compared to haloperidol).[1]. It is an antipsychotic, which can be used for the treatment of schizophrenia[2], but it is primarily used to control antisocial hypersexual behaviour[3], and is sometimes prescribed to sex offenders as a condition of their parole, as an alternative to anti-androgen drugs such as cyproterone.[4]

Benperidol was discovered at Janssen Pharmaceutica in 1961.

References

Cite error: Invalid <references> tag; parameter "group" is allowed only.

Use <references />, or <references group="..." />



bar:Benperidol

de:Benperidol

ru:Бенперидол
  1. Möller; Müller; Bandelow: Neuroleptika, 2001, WVG; ISBN 3-8047-1773-X (in German)
  2. Bobon J, Collard J, Lecoq R, Benperidol and promazine: a "double blind" comparative study in mental geriatrics, Acta Neurol Belg. 1963 Oct;63:839-43.
  3. British National Formulary (49th), British Medical Association 2005 p 183
  4. Murray MA, Bancroft JH, Anderson DC, Tennent TG, Carr PJ., Endocrine changes in male sexual deviants after treatment with anti-androgens, oestrogens or tranquillizers, Journal of Endocrinology. 1975 Nov;67(2):179-88.