Ciramadol

From Self-sufficiency
Revision as of 14:54, 29 July 2010 by PotatoBot (Talk) (Stub sorting and placement of stub template(s))

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Ciramadol
File:Ciramadol.png
Systematic (IUPAC) name
3-[(R)-dimethylamino-[(1R,2R)-2-hydroxycyclohexyl]methyl]phenol
Clinical data
Routes of
administration		 Oral
Identifiers
CAS Number 63269-31-8
ATC code none
PubChem CID 44463
Synonyms Ciramadol, WY-15705
Chemical data
Formula C15H23NO2
Molar mass 249.349 g/mol[[Script error: No such module "String".]]
Script error: No such module "TemplatePar".Expression error: Unexpected < operator.

Ciramadol (WY-15,705) is an opioid analgesic that was developed in the late 1970s and is related to tramadol, tapentadol and venlafaxine.[1] It is a mixed agonist-antagonist for the μ-opioid receptor with relatively low abuse potential[2] and a ceiling on respiratory depression[3] which makes it a relatively safe drug. It has a slightly higher potency and effectiveness as an analgesic than codeine,[4] but is weaker than morphine.[5] Other side effects include sedation and nausea but these are generally less severe than with other similar drugs.[6]

See also

References

Cite error: Invalid <references> tag; parameter "group" is allowed only.

Use <references />, or <references group="..." />


Opioids
See also: Opioids template
Opium & alkaloids thereof
Semi-synthetic opium
derivatives
Synthetic opioids
Pyrazolones
Cannabinoids
Anilides
Non-steroidal
anti-inflammatories
See also: NSAIDs template
Propionic acid class
Oxicam class
Acetic acid class
Anthranilic acid
(fenamate) class
Atypical, Adjuvant & Potentiators,
Metabolic agents and miscellaneous


40px This analgesic-related article is a stub. You can help ssf by expanding it.
  1. ↑ Cochrane AD, Bell R, Sullivan JR, Shaw J. Ciramadol. A new analgesic. Medical Journal of Australia. 1979 Nov 3;2(9):501-2.
  2. ↑ Preston KL, Bigelow GE, Liebson IA. Comparative evaluation of morphine, pentazocine and ciramadol in postaddicts. Journal of Pharmacology and Experimental Therapeutics. 1987 Mar;240(3):900-10.
  3. ↑ Romagnoli A, Keats AS. Low ceiling respiratory depression by ciramadol. International Journal of Clinical Pharmacology Research. 1986;6(6):451-5.
  4. ↑ Downing JW, Brock-Utne JG, Holloway AM. Ciramadol - a new synthetic analgesic. A double-blind comparison with oral codeine for postoperative pain relief. South African Medical Journal. 1983 Dec 10;64(25):978-82.
  5. ↑ Powell WF. A double-blind comparison of multiple intramuscular doses of ciramadol, morphine, and placebo for the treatment of postoperative pain. Anesthesia and Analgesia. 1985 Nov;64(11):1101-7.
  6. ↑ Stambaugh JE Jr, McAdams J. Comparison of the analgesic efficacy and safety oral ciramadol, codeine, and placebo in patients with chronic cancer pain. Journal of Clinical Pharmacology. 1987 Feb;27(2):162-6.
Retrieved from "http://ssf.f15ijp.com/wiki/index.php?title=Ciramadol&oldid=23261"