WAY-267,464

WAY-267,464
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Systematic (IUPAC) name
	4-(3,5-dihydroxybenzyl)-N-(2-methyl-4-[(1-methyl-4,10-dihydropyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]benzyl)piperazine-1-carboxamide
Clinical data
Routes of; administration	?
Legal status
Legal status	Uncontrolled;
Identifiers
CAS Number	847375-16-0
ATC code	none
PubChem	CID 9938214
Chemical data
Formula	C32H35N7O4
Molar mass	581.663 g/mol[[Script error: No such module "String".]]
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WAY-267,464 is a drug which acts as a high affinity, potent, selective, and non-peptide agonist for the oxytocin receptor, with negligible affinity for the vasopressin receptors.^[1]^[2] It has been shown to cross the blood-brain-barrier to a significantly greater extent than exogenously applied oxytocin, and in animal tests produces centrally-mediated oxytocinergic actions such as anxiolytic effects, but with no antidepressant effect evident.^[3]

References

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↑ Rahman Z, Resnick L, Rosenzweig-Lipson SJ, Ring RH,"Methods of treatment using oxytocin receptor agonists", US patent application 2007/0117794, published 2007-05-24 , assigned to Wyeth Corp
↑ Manning M, Stoev S, Chini B, Durroux T, Mouillac B, Guillon G (2008). "Peptide and non-peptide agonists and antagonists for the vasopressin and oxytocin V1a, V1b, V2 and OT receptors: research tools and potential therapeutic agents". Progress in Brain Research. 170: 473–512. doi:10.1016/S0079-6123(08)00437-8. PMID 18655903.
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