SKF-82,958
From Self-sufficiency
File:SKF 82958.png | |
Systematic (IUPAC) name | |
---|---|
3-allyl-6-chloro-1-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol | |
Identifiers | |
CAS Number | 80751-65-1 |
PubChem | CID 1225 |
ChemSpider | 1188 |
Chemical data | |
Formula | C19H20ClNO2 |
Molar mass | 329.82 g/mol |
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SKF-82,958 is a synthetic compound of the benzazepine class that acts as a D1/D5 receptor full agonist.[1][2] SKF-82,958 and similar D1-like-selective full agonists like SKF-81,297 and 6-Br-APB produce characteristic anorectic effects, hyperactivity and self-administration in animals, with a similar but not identical profile to that of dopaminergic stimulants such as amphetamine.[3][4][5][6][7][8][9][10][11]
References
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- ↑ Pfeiffer, Francis R.; Wilson, James W.; Weinstock, Joseph; Kuo, George Y.; Chambers, Pamela A.; Holden, Kenneth G.; Hahn, Richard A.; Wardell, Joseph R., Jr.; Alfonso, J. Tobia; et al. (1982). "Dopaminergic activity of substituted 6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines". Journal of Medicinal Chemistry. 25 (4): 352–358.
- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
- ↑ Terry P, Katz JL (1992). "Differential antagonism of the effects of dopamine D1-receptor agonists on feeding behavior in the rat". Psychopharmacology. 109 (4): 403–9. PMID 1365854.
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