RTI-31
From Self-sufficiency
File:Chlorophenyltropane.png | |
Systematic (IUPAC) name | |
---|---|
methyl (1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate | |
Identifiers | |
CAS Number | 130342-80-2 |
PubChem | CID 131195 |
Chemical data | |
Formula | C16H20ClNO2 |
Molar mass | 293.12 g/mol[[Script error: No such module "String".]] |
Script error: No such module "collapsible list". |
(–)-2β-Carbomethoxy-3β-(4'-chlorophenyl)tropane (RTI-31) is a synthetic analog of cocaine that acts as a stimulant.[1] Semi-synthesis of this compound is dependent upon the availability of cocaine starting material.
Further chemical modification of RTI-31 leads to novel chemical entities; some of them are highly potent, and one of them has been reported as lasting for three days.[2]
RTI-31 is also used in the synthesis of other compounds such as RTI-113 and RTI-336.
References
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See also
This pharmacology-related article is a stub. You can help ssf by expanding it. |
- ↑ Wee, S.; Carroll, F.; Woolverton, W. (2006). "A reduced rate of in vivo dopamine transporter binding is associated with lower relative reinforcing efficacy of stimulants". Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 31 (2): 351–362. doi:10.1038/sj.npp.1300795. PMID 15957006. More than one of
|author2=
and|last2=
specified (help); More than one of|author3=
and|last3=
specified (help) - ↑ Kozikowski, AP; Eddine Saiah, MK; Johnson, KM; Bergmann, JS (1995). "Chemistry and biology of the 2 beta-alkyl-3 beta-phenyl analogues of cocaine: subnanomolar affinity ligands that suggest a new pharmacophore model at the C-2 position". Journal of Medicinal Chemistry. 38 (16): 3086–93. doi:10.1021/jm00016a012. PMID 7636872.
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