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style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers
CAS number 59-61-0
PubChem 443400 (1RYesY, 6951395 (1SYesY, 5806 () YesY
ChemSpider 391627 (1RYesY, 5324297 (1SYesY, 5601 () YesY
KEGG C11772
MeSH Dichloroisoproterenol
ChEBI 144234
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InChI Script error: No such module "collapsible list".
style="background: #F8EABA; text-align: center;" colspan="2" | Properties
Molecular formula C11H15Cl2NO
Molar mass 248.15 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Dichloroisoprenaline (DCI), also known as dichlorosisoproterenol, was the first beta blocker ever to be developed. It is non-selective for the β1-adrenergic and β2-adrenergic receptors. DCI has low potency and acts as a partial agonist/antagonist at these receptors.

Although DCI was of no clinical value itself, further developments from DCI eventually led to the development of the clinical candidate pronethalol (withdrawn due to carcinogenicity) and subsequently propranolol (the first clinically-successful beta blocker).

Dichloroisoprenaline is a racemic mixture of enantiomers.


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