Guanabenz

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Guanabenz
File:Guanabenz.svg
File:Guanabenz sf.png
Systematic (IUPAC) name
2-(2,6-dichlorobenzylidene)hydrazinecarboximidamide
Clinical data
Pregnancy
category
  • US: C (Risk not ruled out)
Pharmacokinetic data
Protein binding 90%
Biological half-life 6 hours
Identifiers
CAS Number 5051-62-7
ATC code none
PubChem CID 3517
DrugBank APRD00487
Chemical data
Formula C8H8Cl2N4
Molar mass 231.081 g/mol[[Script error: No such module "String".]]
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Guanabenz (pronounced GWAHN-a-benz, sold under the trade name Wytensin) is an alpha agonist of the alpha-2 type that is used as an antihypertensive drug. It is used to treat high blood pressure (hypertension).

The most common side effects during guanabenz therapy are dizziness, drowsiness, dry mouth, headache and weakness.

Guanabenz can make one drowsy or less alert, therefore driving or operating dangerous machinery is not recommended.

Sympatholytic (and closely related) antihypertensives (C02)
Sympatholytics
(antagonize α-adrenergic
vasoconstriction)
Central
Adrenergic release inhibitors
Peripheral
Indirect
Direct
Non-selective α blocker
Other antagonists
dual (Bosentan) • selective (Ambrisentan, Sitaxentan)


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