SR 59230A
From Self-sufficiency
| SR 59230A | |
|---|---|
| File:SR 59230A.svg | |
| (2S)-1-(2-ethylphenoxy)-3-{[(1S)-1,2,3, 4-tetrahydronaphthalen-1-yl]amino}propan-2-ol | |
| style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers | |
| CAS number | 174689-39-5 |
| PubChem | 5311452 |
| IUPHAR ligand | 547 |
| SMILES | Script error: No such module "collapsible list". |
| style="background: #F8EABA; text-align: center;" colspan="2" | Properties | |
| Molecular formula | C21H27NO2 |
| Molar mass | 325.44 g mol−1 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) | |
| Infobox references | |
SR 59230A is a selective antagonist of the beta-3 adrenergic receptor,[1][2][3] but subsequently shown to also act at α1 adrenoceptors at high doses.[4] It has been shown to block the hyperthermia produced by MDMA in animal studies.[5]
References
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- ↑ Nisoli E, Tonello C, Landi M, Carruba MO (1996). "Functional studies of the first selective β3-adrenergic receptor antagonist SR 59230A in rat brown adipocytes". Mol. Pharmacol. 49 (1): 7–14. PMID 8569714.
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