Amitraz

Amitraz
File:Amitraz skeletal.svg
IUPAC name N,N'-[(methylimino)dimethylidyne]di-2,4-xylidine
style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers
CAS number	33089-61-1
PubChem	36324
ChemSpider	33405
ATCvet code	QP53AD01
SMILES
InChI
InChI key	QXAITBQSYVNQDR-ZIOPAAQOBL
style="background: #F8EABA; text-align: center;" colspan="2" | Properties
Molecular formula	C19H23N3
Molar mass	293.41 g/mol
Melting point	86–87°C
Solubility in water	Insoluble
Vapor pressure	2.6 x 10-6 mm Hg.
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Amitraz is an antiparasitic drug. Product names include Ridd, Aazdieno, Acarac, Aludex, Amitraze, Avartin, Baam, Edrizan, Maitac, Mitac, Mitaban, Triatox, Triatix, Vapcozin Taktic, Triazid, Topline, Tudy, Ectodex, Garial, Danicut, Ovidrex, Acadrex, Bumetran, and Ovasyn.

It is an alpha-adrenergic agonist.

Uses

Amitraz is a triazapentadiene compound, a member of the amidine class. It is an insecticide and acaricide used to control red spider mites, leaf miners, scale insects, and aphids in which the mechanism of action is similar to other α2-adrenoreceptors agonists as well as by the inhibition of the enzyme monoamine oxidase. Sedation, analgesic effects and cardiovascular depression similar to the α2-adrenoreceptors agonists have been described in several species after amitraz injection. On cotton it is used to control bollworms, white fly, and leaf worms. On animals it is used to control ticks, mites, lice and other animal pests. The United States Environmental Protection Agency classifies amitraz as Class III - slightly toxic.

It cannot be used on horses, because it can cause irreversible gut stasis.

External links

• Amitraz profile from EXTOXNET, maintained by Cornell University

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