Iodocyanopindolol

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Iodocyanopindolol
File:Iodocyanopindolol.png
Systematic (IUPAC) name
(RS)-4-[2-hydroxy-3-(isopropylamino)propoxy]-3-iodo-1H-indole-2-carbonitrile
Identifiers
CAS Number 83498-72-0
ATC code none
PubChem CID 68618
IUPHAR/BPS 540
Chemical data
Formula C15H18IN3O2
Molar mass 399.227 g/mol[[Script error: No such module "String".]]
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Iodocyanopindolol (INN) is a drug related to pindolol which acts as both a β1 adrenoreceptor antagonist and a 5-HT1A receptor antagonist. Its 125I radiolabelled derivative has been widely used in mapping the distribution of beta adrenoreceptors in the body.[1]

References

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  1. Brodde OE, Karad K, Zerkowski HR, Rohm N, Reidemeister JC. Coexistence of beta 1- and beta 2-adrenoceptors in human right atrium. Direct identification by (+/-)-[125I]iodocyanopindolol binding. Circulation Research. 1983 Dec;53(6):752-8. PMID 6139182