Cyclorphan

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Cyclorphan
File:Cyclorphan structure.svg
Systematic (IUPAC) name
3-hydroxy-N-cyclopropylmethylmorphinan
Identifiers
CAS Number 4163-15-9
PubChem CID 5359966
ChemSpider 4514407
Chemical data
Formula C20H27NO
Molar mass 297.434 g/mol[[Script error: No such module "String".]]
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Cyclorphan is a hallucinogenic opioid mixed agonist-antagonist related to levorphanol discovered in the late 1960s. It is not marketed as an analgesic because of side effects related to its impact on the kappa opioid receptor,[1][2] but has found some use as a research chemical on and off since its discovery.

References

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  1. ↑ Herling S, Hein DW, Nemeth MA, Valentino RJ, Woods JH. Discriminative stimulus, antagonist, and rate-decreasing effects of cyclorphan: multiple modes of action. Life Sciences. 1982 Jan 25;30(4):331-41. PMID 6122153
  2. ↑ Bertalmio AJ, Woods JH. Discriminative stimulus effects of cyclorphan: selective antagonism with naltrexone. Psychopharmacology (Berlin). 1992;106(2):189-94. PMID 1347952
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