From Self-sufficiency
Jump to: navigation, search
style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers
CAS number 69587-11-7
PubChem 10267191
ChemSpider 8442670
SMILES Script error: No such module "collapsible list".
InChI Script error: No such module "collapsible list".
style="background: #F8EABA; text-align: center;" colspan="2" | Properties
Molecular formula C10H14INO2
Molar mass 307.13 g mol−1
Melting point

246 °C

Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

2C-I or 2,5-dimethoxy-4-iodophenethylamine is a psychedelic drug and phenethylamine of the 2C family.[1] It was first synthesized by Alexander Shulgin. It was described in Shulgin’s book PiHKAL (Phenethylamines i Have Known And Loved). The drug is used recreationally and as an stimulant or entheogenic but no medical or industrial uses have been reported yet.[citation needed] 2C-I is commonly sold in its hydrochloride salt form which is a fluffy, sparkling white powder, which has also been pressed into tablet form.

Recreational use

In the early 2000s, 2C-I was sold in Dutch smart shops, after 2C-B—which was previously sold—was banned. In April 2003, 2C-I was also banned in the Netherlands, along with three other 2C-x phenethylamines previously sold in Dutch smartshops for short periods of time. During the same period, 2C-I also became available in powder form from several online vendors of research chemicals in the United States, Asia, and Western-Europe. In 2002 and 2003, tablets of 2C-I were being sold in nightclubs and at raves in Denmark and in the United Kingdom as a club drug.[2]

2C-I is generally taken orally, although it can also be insufflated (though 2C-I often causes considerable pain upon insufflation) or administered rectally as well. There have also been a few reports of intramuscular and intravenous injections. Intravenous doses should not be self administered due to the immediate onset of hallucinations and strong physical stimulation before the needle's plunger is fully depressed. An oral recreational dose of 2C-I is commonly between 10 mg and 25 mg, although doses as low as 2 mg have been reported to be active.


The onset of effects usually occurs within two hours, and the effects of the drug typically last somewhere in the range of 4 to 12 hours (depending on the dose). The effects of the drug at small dosages (less than 12 mg) has been reported as more mental and less sensory than those of 2C-B. Users of 2C-I do, however, tend to report a physical stimulant effect, often quite strong and clean.[3] The effects of the drug at larger dosages (12-30+ mg) are often described as combining psychedelic or hallucinogenic effects typical of drugs such as LSD with the empathogenic or entactogenic effects of drugs such as MDMA (ecstasy). Although unpleasant physical side effects such as muscle tension, nausea, and vomiting have been reported, their incidence in the use of 2C-I appears to be less common than in the use of some of the other closely related phenethylamines such as 2C-T-2 and 2C-T-7.

Side effects

2C-I tablet from Denmark

No deaths have been attributed to the drug and several large doses (100+ milligrams) have been survived. There have been no reports of physical dependence or addiction, which is predictable, as chemically similar compounds have exhibited little potential for dependency. 2C-I may include iodine, which can cause thyroid damage. Large doses of 2C-I, like other phenylalanines, may result in undesirable psychological effects, the persistence and severity of which are largely undocumented.

However, some users report short-term diarrhea after ingestion also about an hour later. Nausea is expected. Strong and uncontrollable sexual impulses, violent expressions, the inability to communicate verbally or audibly receive information, have been observed in males during peak 2ci experiences.


2C-I is an illegal, controlled substance in several European nations, including France, Denmark, Germany, Greece, Ireland, the Netherlands, Poland, Spain and the United Kingdom.[4] In December 2003, the European Council issued a binding order compelling all EU member states to ban 2C-I within three months. 2C-I is unscheduled and unregulated in the United States. It is also a controlled substance in Argentina as well as 2C-B and 2C-T-2.[5]

See also


Cite error: Invalid <references> tag; parameter "group" is allowed only.

Use <references />, or <references group="..." />

External links


ja:2C-I pl:2C-I ru:2C-I fi:2C-I

  1. Erowid Online Books: PiHKAL
  2. US Department of Justice, Drug Enforcement Agency
  3. TheSite.org, 2009
  4. Erowid.org, Legal Status of 2C-I
  5. Last Argentina Controlled Drugs List