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Systematic (IUPAC) name
Legal status
Legal status
CAS Number 2235-90-7 118-68-3 (acetate)
ATC code none
PubChem CID 8367
ChemSpider 8064
Synonyms 3-(2-aminobutyl)indole
Chemical data
Formula C12H16N2
Molar mass 188.27 g/mol[[Script error: No such module "String".]]
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Physical data
Melting point 222 to 223 °C (432 to 433 °F)
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α-ethyltryptamine (αET, AET, "Monase"), also known as etryptamine, is a psychedelic, stimulant and entactogen of the tryptamine chemical class.


Originally believed to exert its effects predominantly via monoamine oxidase inhibition, alpha-ethyltryptamine was developed as an antidepressant by Upjohn chemical company in the United States under the name "Monase" but was withdrawn from potential commercial use due to an unacceptable incidence of agranulocytosis.[1]

αET was abused as a designer drug in the 1980s. Subsequently, in the USA it was added to the Schedule I list of illegal substances in 1993.


αET is structurally and pharmacologically related to α-methyltryptamine (αMT), but its effects are slightly different. In contrast to αMT, αET is less stimulating and hallucinogenic, its effects resembling more those of entactogens like MDMA ("Ecstasy").

Similarly to MDMA, αET has been demonstrated to be a releasing agent of serotonin, norepinephrine and dopamine (with serotonin being the primary neurotransmitter affected); in addition, it acts as a non-selective serotonin receptor agonist. Scientific research has shown that alpha-ethyltryptamine is a serotonergic neurotoxin.[2]

See also


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External links



  1. α-ET TiHKAL entry • Erowid.
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